The applications of Ion Beam Analysis to art and archeology back almost to the beginnings of the development of PIXE (Particle Induced X-ray Emission), with study of ceramic fragments and obsidian tools. They were then quickly extended to all cultural heritage materials. However, these techniques are more suited to certain materials than others, such as those made of thin layers of high atomic number elements on a substrate of low atomic number elements (light elements), This is the case of drawings and illuminations