Cardiac scintigraphies

Tests of the cardiac muscle functionning


Principle and test implementation

Myocardial scintigraphy by perfusion can assess blood flow to the heart muscle (evaluation of the infusion) and provides information on its function and capabilities of contraction.

Myocardial scintigraphy
Myocardial scintigraphy was designed to assess blood flow in the heart muscles (perfusion assessment) and provide information on its mechanism. It is estimated by operating through tomographic section of cardiac volume done according to three planes, comparing the acquisitions made after an exercise test and rest. Here we see two of the cuts made to plans known as "small vertical" and "large vertical” axis.
CHU Avicenne
Myocardial scintigraphy: large horizontal axis sections
Completion of the previous diagram, this one shows the same cardiac test, sections of the heart according to the third plane, known as the transverse plane. A doctor who makes a diagnostic gets a natural access to three sets of sections at the same time.
CHU Avicenne

The comparison of the radiotracer fixation in the heart muscle for two situations, one during effort and one at rest is used to diagnose or exclude heart disease.

The first phase of the review is therefore to perform a stimulation test (effort on bicycle and / or pharmacological test) to assess cardiac perfusion under stress. At the end of stimulation the radiopharmaceutical is injected intravenously and an tomographic acquisition under multiple angles is completed.

The second phase of the examination is performed 3-4 hours after the acquisition effort to evaluate the cardiac perfusion at rest.

Indications of cardiac scintigraphy by perfusion:
- Myocardial infarct: diagnosis, localization and extent of necrosis, looking for residual ischemia;
- Coronary artery: diagnosis, assessment and monitoring;
- Cardiomyopathies: differential diagnosis, prognosis.

Radiopharmaceuticals most frequently used:
- Thallium-201 (201Tl) period 72 hours ;
- Technetium-99m (Tc99m MIBI) period 6 hours.


Principle and test implementation
The ventriculography with radionuclide allows the analysis of the volume of cardiac cavities (normal or dilated),and of its global or segmental contractility (ejection fraction).

Main indication of radionuclide ventriculography:
- Measurement of left ventricular ejection fraction (LVEF)
Radiopharmaceuticals used:
- Albumin tagged with Technetium-99m
- Marking of erythrocytes (pyrophosphate technetium-99m pertechnetate +)

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